Talk:Sucralose

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Side Effects

This article neglects to mention possible side effects of Sucralose such as its genotoxicity and diarrhea-inducing effects. Many other sources, such as WebMD confirm and discuss such side effects. 65.183.164.194 (talk) 11:44, 27 June 2023 (UTC)[reply]

Feel free to add information about side effects - if you have some reviews complying with WP:MEDRS and WP:BURDEN. Thanks JimRenge (talk) 12:24, 27 June 2023 (UTC)[reply]

A new study suggests serious side effects [[1]] — Preceding unsigned comment added by 84.202.48.248 (talk) 07:36, 29 June 2023 (UTC)[reply]

And there are people out there like me that have a severe allergic reaction to artificial sweeteners, this one included.....so anaphylactic shock is the at the top of the list for me for side effects, and most food companies do NOT list artificial sweeteners as an allergen. 72.240.196.141 (talk) 23:43, 16 May 2024 (UTC)[reply]

Anaphylaxis with sucralose is unknown in the medical literature. If you had a reaction, it is more likely to have been with some confounding nutrient in what you ate or, least likely, with Splenda which is not the same thing as sucralose, in spite of the confusing wording of this article. Splenda has bulking carbs added, hundreds of times the mass of the sucralose proper.

If you did happen to come across actual pure sucralose, the stuff degrades notoriously after exposure to air and turns bitter. A reaction is distantly possible to a degraded substance in the opened container of sucralose, but you'd know when you tasted it. JohndanR (talk) 20:54, 12 September 2024 (UTC)[reply]

Aggressive archiving of discussions on genotoxicity

Be advised: It seems as if there are individuals (some utilizing bots) extremely opposed to both the addition of genotoxicity to the article, as well as the discussion of genotoxicity here on the talk page. Any additions to the article discussing genotoxicity are immediately reverted, and discussions on the talk page are quickly archived. 2600:1008:B21C:8E1D:78BD:46FF:FEEA:87D6 (talk) 04:43, 27 September 2024 (UTC)[reply]

Discussions are archived only if they have been inactive for 90 days. Any medical-related statement added to the article absolutely must be cited to a WP:MEDRS compliant source. Otherwise such statements will be reverted. It's that simple. ~Anachronist (talk) 05:20, 27 September 2024 (UTC)[reply]

Proposed sources

This information needs to be on the page. period.

"The consumption of sucralose, a commonly used artificial sweetener, is associated with various adverse health effects. Despite being considered safe following previous studies, recent research suggests possible links to systemic inflammation, metabolic diseases, disruptions in gut microbiota, liver damage, and toxic effects at the cellular level"

https://pmc.ncbi.nlm.nih.gov/articles/PMC10971371/

https://pubmed.ncbi.nlm.nih.gov/37246822/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10971371/#B7-life-14-00323

Lots of studies regarding the toxicity of sucralose at the cellular level are popping up now. 2601:243:E07F:5F80:9C68:7ACB:B62D:7503 (talk) 20:32, 21 December 2024 (UTC)[reply]

2601:243:*, in wikipedia "Biomedical information must be based on reliable, third-party published secondary sources, and must accurately reflect current knowledge." Per WP:MEDRS, a wikipedia content guideline, acceptable sources include "review articles (especially systematic reviews) published in reputable medical journals, academic and professional books written by experts in the relevant fields and from respected publishers, and guidelines or position statements from national or international expert bodies. Primary sources should generally not be used for medical content, as such sources often include unreliable or preliminary information; for example, early lab results that do not hold in later clinical trials." Your proposed sources should be avoided because https://pubmed.ncbi.nlm.nih.gov/37246822/ is a primary source and the the other 2 sources are from MDPI, a publisher with questionable reputation. JimRenge (talk) 21:02, 21 December 2024 (UTC)[reply]